According to Bartlett et al. (2022), this species is an established human pathogen.Publication:
Bartlett A, Padfield D, Lear L, Bendall R, Vos M. A comprehensive list of bacterial pathogens infecting humans. Microbiology 2022; 168:0.
See also Clermont et al. (2015).Publication:
Clermont O, Gordon D, Denamur E. Guide to the various phylogenetic classification schemes for Escherichia coli and the correspondence among schemes. Microbiology (Reading) 2015; 161:980-988.
The genome of the type strain was sequenced as part of the GEBA (Genomic Encyclopedia of Bacteria and Archaea) project.Publication:
Meier-Kolthoff JP, Hahnke RL, Petersen J, Scheuner C, Michael V, Fiebig A, Rohde C, Rohde M, Fartmann B, Goodwin LA, et al. Complete genome sequence of DSM 30083T, the type strain (U5/41T) of Escherichia coli, and a proposal for delineating subspecies in microbial taxonomy. Stand Genomic Sci 2014; 9:2.
Escherichia coli and the four species of the genus Shigella are a single species on the basis of DNA relatedness. Moreover, these taxa are often difficult to separate biochemically, and pathogenicity does not provide definitive separation (some Escherichia coli strains can cause a dysentery-like diarrhea). However, they remain separate species to avoid confusion in medical microbiology.Publication:
Brenner DJ. Family I. Enterobacteriaceae Rahn 1937, Nom. fam. cons. Opin. 15, Jud. Com. 1958, 73; Ewing, Farmer, and Brenner 1980, 674; Judicial Commission 1981, 104. In: Krieg NR, Holt JG (eds), Bergey's Manual of Systematic Bacteriology, first edition, vol. 1, The Williams & Wilkins Co, Baltimore, 1984, p. 408-420.